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"We had no knowledge on meta‐analyses and were somewhat confused by the number of programs available. Most of them were not easy to use, not insightful and required a priori knowledge of metaanalyses statistics. There was one exception: Comprehensive Meta‐analysis. We downloaded the software and went through the easy‐to‐use tutorial. Within an hour we were performing our own metaanalysis! Our analysis was verified by our statistical department with excellent results, giving us further confidence to continue our analysis and resulting in an excellent paper in the top journal on pain research: Niesters et al., Do Sex Differences Exist in Opioid Analgesia? A Systematic Review and Meta‐ Analysis of Human Experimental and Clinical Studies. Pain, 2010, in press, doi:10.1016/j.pain.2010.06.012."

Albert Dahan, MD, PhD & Marieke Niesters, MD, MSc - Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands


"I have been using Comprehensive Meta‐Analysis for the past five years and have enjoyed the many features of this software including the numerous options for fitting data into the spreadsheet for analysis of categorical and continuous data and the ease of labeling variables and study names. The built in analysis features are many and easy to apply including the test for heterogeneity and Egger’s test for publication bias. This software has allowed me to publish meta‐analyses with confidence in several peer reviewed journals including the Journal of Cardiology. Also I am often asked to give lectures on the use of meta‐analyses. My demonstrations include examples from this program. When asked by my peers for a reliable meta‐analysis package I do recommend this software."

Al Bartolucci, Ph.D. - Professor, Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama

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Comprehensive Meta-Analysis

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Comprehensive Meta-Analysis (CMA) is a powerful computer program for meta-analysis. The program combines ease of use with a wide array of computational options and sophisticated graphics.