"Comprehensive meta‐analysis is so easy to use that a clinician feels absolutely comfortable with it. You only need to have the results from individual studies and follow instructions: you will have calculations and graphs in a way that you can easily interpret. With this software meta‐analysis is not arcane any more: if you can read papers based on this statistical technique you will be able to write them as well."

Prof. Luis Garcia‐Marcos - Professor of Pediatrics, University of Murcia, Spain

"We had no knowledge on meta‐analyses and were somewhat confused by the number of programs available. Most of them were not easy to use, not insightful and required a priori knowledge of metaanalyses statistics. There was one exception: Comprehensive Meta‐analysis. We downloaded the software and went through the easy‐to‐use tutorial. Within an hour we were performing our own metaanalysis! Our analysis was verified by our statistical department with excellent results, giving us further confidence to continue our analysis and resulting in an excellent paper in the top journal on pain research: Niesters et al., Do Sex Differences Exist in Opioid Analgesia? A Systematic Review and Meta‐ Analysis of Human Experimental and Clinical Studies. Pain, 2010, in press, doi:10.1016/j.pain.2010.06.012."

Albert Dahan, MD, PhD & Marieke Niesters, MD, MSc - Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands