"I can confirm that comprehensive meta‐analysis is a very valuable tool for analyzing data. In one of my most important publications the use of forest plots constructed with Comprehensive Meta‐analysis has contributed to the success of this article. As a clinician my statistical background is not as strong as I would like it to be. However, using CMA is very straightforward and I was able to astonish my epidemiologist co‐author. I can recommend Comprehensive Meta‐Analysis to any clinical researcher."

Harm J T Rutten, MD, PhD, FRCS (London) - Head, Department Surgical Oncology, Catharina Hospital, Eindhoven, The Netherlands

"We had no knowledge on meta‐analyses and were somewhat confused by the number of programs available. Most of them were not easy to use, not insightful and required a priori knowledge of metaanalyses statistics. There was one exception: Comprehensive Meta‐analysis. We downloaded the software and went through the easy‐to‐use tutorial. Within an hour we were performing our own metaanalysis! Our analysis was verified by our statistical department with excellent results, giving us further confidence to continue our analysis and resulting in an excellent paper in the top journal on pain research: Niesters et al., Do Sex Differences Exist in Opioid Analgesia? A Systematic Review and Meta‐ Analysis of Human Experimental and Clinical Studies. Pain, 2010, in press, doi:10.1016/j.pain.2010.06.012."

Albert Dahan, MD, PhD & Marieke Niesters, MD, MSc - Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands