"We had no knowledge on meta‐analyses and were somewhat confused by the number of programs available. Most of them were not easy to use, not insightful and required a priori knowledge of metaanalyses statistics. There was one exception: Comprehensive Meta‐analysis. We downloaded the software and went through the easy‐to‐use tutorial. Within an hour we were performing our own metaanalysis! Our analysis was verified by our statistical department with excellent results, giving us further confidence to continue our analysis and resulting in an excellent paper in the top journal on pain research: Niesters et al., Do Sex Differences Exist in Opioid Analgesia? A Systematic Review and Meta‐ Analysis of Human Experimental and Clinical Studies. Pain, 2010, in press, doi:10.1016/j.pain.2010.06.012."

Albert Dahan, MD, PhD & Marieke Niesters, MD, MSc - Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands

"I am impressed with the ease or simplicity of the Comprehensive Meta‐Analysis, not only in data entry but also the data generated. Unlike some of the free software available for meta‐analysis, I found the Comprehensive Meta‐Analysis user‐friendly, generating clear graphs and effect sizes. I took a long time to work out some of the free software available by some of my colleagues and found them very userunfriendly, confusing, and the graphs generated not easy on the eye. After chancing on Comprehensive Meta‐Analysis during a Google search and having a go at it during the free trial, I was keen to get my hands on it and have recommended it to some of colleagues. It is definitely worth getting it as it makes meta‐analysis non‐daunting and non‐scary especially for students pursuing their Masters or PhDs."

Li Whye Cindy, NG