"We bought the CMA software for professional perpetual version at the beginning of this year, and we have used it to do meta-analyses for several studies and trained the postgraduate students already. The friendly spreadsheet, easy-understandable dialog, not programming and modifiable output style make use of the software to do a meta-analysis convenient. The most fabulous point is that it can extend the traditional comparison of two groups to estimation of effect size in one group and generic point estimates. In summary, this software is an efficient and user-friendly tool for scientists to do a study related to meta-analysis."

Xiang-Sheng Chen, MD, PhD - Professor and Vice Director, National Center for STD Control, China CDC Nanjing 20042, China

"We had no knowledge on meta‐analyses and were somewhat confused by the number of programs available. Most of them were not easy to use, not insightful and required a priori knowledge of metaanalyses statistics. There was one exception: Comprehensive Meta‐analysis. We downloaded the software and went through the easy‐to‐use tutorial. Within an hour we were performing our own metaanalysis! Our analysis was verified by our statistical department with excellent results, giving us further confidence to continue our analysis and resulting in an excellent paper in the top journal on pain research: Niesters et al., Do Sex Differences Exist in Opioid Analgesia? A Systematic Review and Meta‐ Analysis of Human Experimental and Clinical Studies. Pain, 2010, in press, doi:10.1016/j.pain.2010.06.012."

Albert Dahan, MD, PhD & Marieke Niesters, MD, MSc - Department of Anesthesiology, Leiden University Medical Center, Leiden, The Netherlands