"The program in Comparative Effectiveness and Outcomes Research at Duke University conducts multiple systematic reviews and meta‐analyses each year for professional organizations as well as under both federal and industry sponsored research initiatives. While we use various programs tailored for specific individual projects including those developed in‐house, we have found Comprehensive Meta‐Analysis (CMA) to be a very facile, adaptable and yet comprehensive package meeting the needs for much of our research and generating publication‐quality graphics. My confidence in the analytic algorithms is buoyed by my knowledge of several of the developers of CMA and based on extensive comparison of results with other algorithms including our own. CMA is also an exceptional educational tool and universally embraced by trainees and young investigators initiating careers in evidence‐based medicine and statistical analysis."

Gary H Lyman, MD, MPH, FRCP (Edin) - Professor of Medicine and Director, Comparative Effectiveness and Outcomes Research, Duke University School of Medicine, and the Duke Comprehensive Cancer Center, Senior Fellow, Duke Center for Clinical Health Policy Research, Durham, NC

"Comprehensive Meta‐Analysis is a fabulous program for research synthesis, combining ease of use with advanced features not available in standard statistical packages or competing stand‐alone products. The program is ideal for independent analysis or reanalyzing data from another published review (including Cochrane reviews) to explore subgroups, moderator variables, and clinically relevant measures of effect size. Forest and funnel plots can be easily created and customized for publicationquality graphics. As editor in chief of Otolaryngology – Head and Neck Surgery, I find the program indispensable for preparing a quarterly installment, The Cochrane Corner, which highlights a relevant Cochrane review and provides expert commentary to aid clinicians in applying and understanding the results. I strongly recommend this program to novice and experienced meta‐analysts alike."

Richard M. Rosenfeld, MD, MPH - Professor and Chairman of Otolaryngology, SUNY Downstate Medical Center, Brooklyn, NY, Journal Editor and Chair, Guideline Development Task Force, American Academy of Otolaryngology – Head and Neck Surgery